Beverley Orser
Affiliate scientist
Sunnybrook Research Institute


Research Interests: Neuroscience, mechanisms of anesthetic and GABAA receptor physiology

Bio Brief

Dr. Orser's scientific research is driven by several fundamental questions: how do general anesthetics work, what are their adverse effects and how can such adverse effects be prevented? Her team is currently studying how anesthetic drugs cause the profound memory loss that is required during surgery and how they contribute to long-term cognitive deficits that occur in patients the postoperative period. Dr. Orser’s laboratory was the first to demonstrate the unique pharmacological properties of extrasynaptic GABAA receptors and the exquisite sensitivity of these receptors to general anesthetic drugs. These receptors are now being targeted for novel treatments for a variety of neurological disorders including cognitive deficits, chronic pain and depression.

Other Highlights:

HIIO (Health Innovation Implementation in Ontario), an Online Resource for Health Innovators in Ontario

Written by: Paige Gilbank “Canada is a leader for the development of innovative health technologies. However, in Ontario, there are no widely accepted, consistent pathways or processes for implementation and many seemingly great innovations fail to penetrate our...

Found in Translation: You have a great invention and you disclose it at a conference… Now what?

 By Gabriella Chan    On June 11, 2018 the United States Federal Court of Appeals (the “Court”) heard the case of Medtronic Inc. v. Mark Barry. Medtronic is a global manufacturer of various medical devices including spinal surgery tools and devices. Spinal surgeon Dr....

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