Berge Minassian
Staff Neurologist
Neurology, The Hospital for Sick Children


Research Interests: Subject Area Themes: Lafora disease, X-linked myopathy with excessive autophagy, Rett Syndrome

Bio Brief

Dr. Minassian has the rank of Professor and directs a lab with nine trainees and technicians at SickKids.  His lab has helped discover seven disease genes, including four for epilepsy.  His most active research area is the unraveling of the pathogenesis of Lafora disease.  His lab has disclosed a novel pathway of regulation of glycogen synthesis involving the Lafora disease genes.  Dr. Minassian’s group has made seminal contributions to Rett and Angelman syndromes, the most common forms of mental retardation with epilepsy.  His lab also discovered the first two canine epilepsy genes.  Dr. Minassian holds the University of Toronto Michael Bahen Chair in Epilepsy Research and co-directs a nationwide epilepsy project funded by Genome Canada involving whole genome sequencing of 2000 epileptic patients to identify the genetic bases of epilepsy and intractable epilepsy.

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