Director, Arthritis Centre of Excellence

Research Interests: Ankylosing Spondylitis is an autoimmune arthritis which is the most common form of inflammatory joint disease affecting the spine. The Spondylitis Program at TWH plays a leading role in defining the genetic basis of this disease, developing new outcome measures, and introducing innovative new biologic agents for the treatment of this disease. Reactive Arthritis is a form of arthritis that is triggered by an infection. Through studies of epidemic outbreaks across Canada, these studies address the interaction of genetic and environmental factors that interact in the development of autoimmunity. Immunology of Infection holds the promise of defining the genetic control of defence against bacterial infections. These studies represent translational research, which incorporates clinical studies, experimental models of arthritis, and basic cellular and molecular immunology.
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