MD, PhD, FRCSC, FACS
Dr. Macdonald's major research interests are in the field of aneurismal subarachnoid hemorrhage and cerebral vasospasm. We are investigating causes of delayed neurological deterioration after subarachnoid hemorrhage using animal models and testing hippocampal electrophysiology and function, animal behavior, learning and memory and changes in gene expression and function. We also are studying mechanisms of large artery vasospasm after aneurismal subarachnoid hemorrhage and effects of intracerebral and subdural hemorrhage on the brain. All of this work is laboratory-based as well as clinical with clinical trials and patient-based studies conducted testing similar hypotheses.
Subject Area Themes: Subarachnoid hemorrhage, cerebral vasospasm, cerebral blood flow and metabolism, stroke, cerebral aneurysms, cerebrovascular malformations, chronic subdural hematoma, intracerebral hemorrhage
Division of Neurosurgery, St. Michael's Hospital
"The program combines not only research and science but also policy and business, which are very important aspects of translational research.”
- Helen Liu, Cohort 2017