Women who inherit a mutation in one of the two breast cancer susceptibility genes – BRCA1 or BRCA2 – have an increased risk of developing breast and ovarian cancer. Despite the fact that these genes were identified over 20 years ago, surgical prevention remains the most effective strategy for these high-risk women. Joanne Kotsopoulos, PhD and Tier 2 Canada Research Chair in Hereditary Breast and Ovarian Cancer Prevention, is investigating these hereditary cancers at the genetic level to deliver evidence-based, personalized strategies to improve women’s health and lower cancer incidence and mortality rates around the world.
Women's College Research Institute
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