March 6, 2015

What exactly is translational research?

What exactly is translational research?

  • Translational research is defined as the application of scientific discoveries, clinical insights or policy initiatives into problem-solving designs that enhance human health and well-being. However, definitions can vary widely between disciplines, institutions and experts. [Read more]
  • The National Center for Advancing Translational Sciences (NCATS) in the United States NCATS defines Translation as: [the] process of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public….
  • We view translational research as: systematic investigation, study and knowledge production that turns observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public.
  • TR can be seen as the spectrum of innovation in health science encompassing the “P”s” of impact for healthy communities:
    • People – the translation of research from models into humans.
    • Patients/populations – health promotion and solutions for healthier communities.
    • Policy – findings that shape policy in a broad way.
    • Products – the development of products that assist with health care.
    • Processes or procedures – the development of processes or procedures, such as new screening processes for diseases that benefit individual patients and physicians – i.e. diagnostic techniques.
    • Pharmaceuticals– medicinal chemistry and issues of drug delivery.
    • Pathways—the biochemical and genetic sources of variation in disease presentation that underscore concepts of personalized medicine.

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