Translational research is defined as the application of scientific discoveries, clinical insights or policy initiatives into problem-solving designs that enhance human health and well-being. However, definitions can vary widely between disciplines, institutions and experts. [Read more]
The National Center for Advancing Translational Sciences (NCATS) in the United States NCATS defines Translation as: [the] process of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public….
We view translational research as: systematic investigation, study and knowledge production that turns observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public.
TR can be seen as the spectrum of innovation in health science encompassing the “P”s” of impact for healthy communities:
People – the translation of research from models into humans.
Patients/populations – health promotion and solutions for healthier communities.
Policy – findings that shape policy in a broad way.
Products – the development of products that assist with health care.
Processes or procedures – the development of processes or procedures, such as new screening processes for diseases that benefit individual patients and physicians – i.e. diagnostic techniques.
Pharmaceuticals– medicinal chemistry and issues of drug delivery.
Pathways—the biochemical and genetic sources of variation in disease presentation that underscore concepts of personalized medicine.